no.. i use an iMac.. but they should not be any
different...
PC programs will be dependent on the processor.. if it's the old G4
or G5, cannot..
if it's the newer Intel chips, you can install xp in it and it'll
then run PC programs..
your Mac will then be dual-bootable.. you can run OSX or xp on
it...
mostly, what PC progs do you want your mac to run?